The Roslin Institute

• Professor Alan Archibald
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  • Porcine Genome Sequencing Project
  • Genetics of litter size and foetal loss in pigs
  • Porcine Reproductive and Respiratory Syndrome (PRRS) - genetics of host responses
  • Approaches to functional genomics of host tolerance in vector borne parasitic diseases of cattle

Porcine Genome Sequencing Project

Funded by: USDA CSREES, EC FP6 and others

The pig genome is being sequenced under the auspices of the Swine Genome Sequencing Consortium. A clone-by-clone hierarchical shotgun sequencing strategy is being pursed that exploits the excellent clone-based (BAC contig) physical map of the pig genome. The Wellcome Trust Sanger Institute is the lead sequencing centre for this international collaborative project. Funding is provided by USDA-CSREES, EC FP6 (SABRE), Institute for Pig Genetics and others. The draft sequence is scheduled for completion in late 2009.

Relevant references:

Schook et al., 2005. Swine Genome Sequencing Consortium (SGSC): a strategic roadmap for sequencing the pig genome. Comparative and Functional Genomics 6, 251-255.

Humphray et al., 2007. A high utility integrated map of the pig genome. Genome Biology 8:R139doi:10.1186/gb-2007-8-7 r139. genomebiology.com/2007/8/7/R139

Links:
Swine Genome Sequencing Consortium: piggenome.org/
Porcine Genome Sequencing Project (Sanger): www.sanger.ac.uk/Projects/S_scrofa/
Pig genome sequence in Pre-Ensembl: pre.ensembl.org/Sus_scrofa/Info/Index
Pig physical (BAC contig) map in Pre-Ensembl: pre.ensembl.org/Sus_scrofa_map/Info/Index