Publications
25. Small BG*, McColl BW*, Allmendinger R, Pahle J, López-Castejón G, Rothwell NJ, Knowles J, Mendes P, Brough D, Kell DB (2011) Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing. Nat Chem Biol doi: 10.1038/nchembio.689
*authors contributed equally
24. Ketheeswaranathan P, Turner NA, Spary EJ, Batten TFC, McColl BW, Saha S (2011) Changes in glutamate transporter expression in mouse forebrain areas following focal ischemia. Brain Res 1418:93-103
23. McColl BW, Allan SM, Denes A, Lawrence CB (2011) "Influenza Virus Infection Aggravates Stroke Outcome". Stroke 111:e416
22. Drake C, Boutin H, Jones MS, Denes A, McColl BW, Selvarajah JR, Hulme S, Georgiou RF, Hinz R, Gerhard A, Vail A, Prenant C, Julyan P, Maroy R, Brown G, Smigova A, Herholz K, Kassiou M, Crossman D, Francis S, Proctor SD, Russell JC, Hopkins SJ, Tyrrell PJ, Rothwell NJ, Allan SM (2011) Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain Behav Immun 25:1113-1122
21. Denes A, McColl BW Leow-Dyke S, Chapman KZ, Humphreys N, Grencis R, Allan SM. Rothwell NJ (2011) Experimental stroke induced changes in the bone marrow reveal complex regulation of leukocyte responses. J Cereb Blood Flow Metab 31:1036-1050
20. Thornton P, McColl BW, Cooper L, Rothwell NJ, Allan SM (2010) Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways. Curr Neurovasc Res 7:330-340
19. McColl BW, Howells D, Rothwell NJ, Denes A (2010) Modeling risk factors and confounding effects in stroke. Neuromethods 47:93-119.
18. Parry-Jones A, Boutin H, Denes A, McColl B, Hopkins S, Allan S, Tyrrell P (2010) Interleukin-1 receptor antagonist in animal models of stroke: a fair summing up? J Stroke Cerebrovasc Dis 19:512-513
17. Thornton P, McColl BW, Greenhalgh A, Denes A, Allan SM, Rothwell NJ (2010) Platelet interleukin-1alpha drives cerebrovascular inflammation. Blood 115:3632-3639
16. McColl BW, Rose N, Robson FH, Rothwell NJ, Lawrence CB (2010) Increased brain microvascular MMP-9 and incidence of haemorrhagic transformation in obese mice after experimental stroke. J Cereb Blood Flow Metab 30: 267-272
15. Bano D, Dinsdale D, Cabrera-Socorro A, Maida S, Lambacher N, McColl BW, Ferrando-May E, Hengartner MO, Nicotera P (2010) Alteration of the nuclear pore complex in Ca(2+)-mediated cell death. Cell Death Differ 17: 119-133
14. Luheshi NM, McColl BW, Brough D (2009) Nuclear retention of IL-1alpha by necrotic cells: A mechanism to dampen sterile inflammation. Eur J immunol 39: 2973-2980
13. Chapman KZ, Dale VQ, Denes A, Bennett G, Rothwell NJ, Allan SM, McColl BW (2009) A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke. J Cereb Blood Flow Metab 29:1764-1768
12. McColl BW, Allan SM, Rothwell NJ (2009) Systemic infection, inflammation and acute ischaemic stroke. Neuroscience 158: 1049-1061.
11. McColl BW, Rothwell NJ, Allan SM (2008) Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice. J Neurosci 28: 9451-62
10. McColl BW, Allan SM, Rothwell NJ (2007) Systemic inflammation and stroke: aetiology, pathology and targets for therapy. Biochem Soc Trans 35: 1163-1165. Invited review
09. Wang X, Nadarajah B, Robinson AC, McColl BW, Jin JW, jas-Bailador F, Boot-Handford RP, Tournier C (2007) Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death. Mol Cell Biol 27:7935-7946.
08. Denes A, Vidyasagar R, Feng J, Narvainen J, McColl BW, Kauppinen RA, Allan SM (2007) Proliferating resident microglia after focal cerebral ischaemia in mice. J Cereb Blood Flow Metab 27:1941-1953.
07. McColl BW, Rothwell NJ, & Allan SM (2007). Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms. J Neurosci 27: 4403-4412.
06. Magnoni S, Baker A, Thomson S, Jordan G, George SJ, McColl BW, McCulloch J, & Horsburgh K (2007). Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury. Gene Ther 14: 621-625.
05. McColl BW, McGregor AL, Wong A, Harris JD, Amalfitano A, Magnoni S, Baker AH, Dickson G, & Horsburgh K (2007). APOE epsilon3 gene transfer attenuates brain damage after experimental stroke. J Cereb Blood Flow Metab 27: 477-487.
04. McColl BW, Stock CJ, Rothwell NJ (2007) Cytokines and non-immune brain injury. In: Psychoneuroimmunology, 4th Edition, pp 415-427.
03. McColl BW, Carswell HV, McCulloch J, & Horsburgh K (2004). Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice. Brain Res 997: 15-23.
02. Horsburgh K, McColl BW, White F, & McCulloch J (2003). Apolipoprotein E influences neuronal death and repair. International Congress Series 1252: 171-178.
01. McColl BW, Graham DI, Weir CJ, White F, & Horsburgh K (2003). Endocytic pathway alterations in human hippocampus after global ischemia and the influence of APOE genotype. Am J Pathol 162: 273-281.