Technologies
Much of our work revolves around transferring gene constructs and vectors into cells and animals. This includes application of lentivirus-based vectors.
References:
Whitelaw CBA, Radcliffe PA, Ritchie WA, Carlisle A, Ellard F, Pena R, Rowe J, Clark AJ, King TJ and Mitrophanous KA (2004) Efficient generation of transgenic pigs using equine infectious anaemia virus (EIAV) derived vector. FEBS Lett 571, 233-236.
Whitelaw CBA (2004) Transgenic livestock made easy. Trends Biotech 22, 157-159.
Ritchie WA, Taylor JE, Gardner JO, Wilmut I, Carlisle A, Neil C, King T and Whitelaw CBA (2005) Live lambs born from zona-pellucida denuded embryos. Cloning Stem Cells 7, 178-182.
Ritchie WA, Neil C, King T and Whitelaw CBA (2007) Transgenic mice produced from low titre lentiviral vectors. Transgenic Res. 16, 661-664.
Ritchie WA, King T, Neil C, Carlisle A, Lillico S, McLachalan G and Whitelaw CBA (2009) Transgenic sheep designed for transplantation studies. Mol Reprod Dev. 76, 61-4
Le Provost F, Lillico S, Passet B, Young R, Whitelaw CBA and Vilotte JL (2010) Zinc-finger nuclease systems herald new era in mammalian transgenesis. Trends Biotech 28, 134-141.
Lillico S, Vasey D, King T and Whitelaw B (2011) Lentiviral transgensis in livestock. Transgenic Res 20, 441-442.