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The Roslin Institute

Developmental Biology

Technologies

Facilities for induction and maintenance of general anaesthesia by gaseous or total intravenous infusion

Option for negative or positive pressure mechanical ventilation

Facility to collect bronchoscopic images and real-time digital video footage

Facility to deliver aerosols to the whole lung by ultrasonic, jet or vibrating mesh nebulizer or to the whole or part of the lung by nebulisation catheter

Facility to gate aerosol delivery to a defined proportion of inspiration

Facility to employ positive end expiratory airway pressure or extracorporeal negative end expiratory pressure

Facility to employ variable frequency chest wall oscillation

Facility to monitor and assess physiologic responses including ECG, NiBP, ETCO2 and O2sat

Facility to measure lung physiologic responses including airway reactivity, lung volumes (gas dilution, nitrogen washout), diffusing capacity and pulmonary mechanics (RL, Cdyn) by conventional oesophageal catheter and forced oscillation techniques

Facility to measure lung function at the segmental level - Rcoll

Facility to collect cell or tissue samples from the lung by bronchoalveolar lavage, bronchial brushing and bronchial biopsy

Facility to collect exhaled breath condensate