Visit the BBSRC website (opens in a new window)

The Roslin Institute receives strategic funding from BBSRC

BBSRC News feed

The Roslin Institute

Developmental Biology

Publications

  • Hammond, N.L., Headon, D. & Dixon, M.J. 14-3-3σ is required for hair follicle integrity and epithelial homeostasis. Journal of Investigative Dermatology, E-pub 1 March, 11pp. (2012).
  • Cluzeau, C., Hadj-Rabia, S., Bal, E., Bodemer, C., Clauss, F., Munnich, A., Headon, D., Smahi, A. The EDAR370A allele attenuates the severity of Hypohidrotic Ectodermal Dysplasia caused by EDA1 Gene Mutation. British Journal of Dermatology 166(3), 678-681. (2012).
  • Klika, V., Baker, R. E. Headon, D. The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation. Bulletin of Mathematical Biology 74(4) 935-957 (2012)
  • Kowalczyk, C., Dunkel, N., Willen, L., Casal, M. L., Mauldin, E. A., Gaide, O., Tardivel, A., Badic, G., Etter, A. L., Favre, M., Jefferson, D. M., Headon, D. J.
    Demotz, S., Schneider, P.  Molecular and therapeutic characterization of anti- Ectodysplasin A receptor (EDAR) agonist monoclonal antibodies. J Biol Chem 286(35): 30769-30779. (2011)
  • Mou, C., Pitel, F., Gourichon, D., Vignoles, F., Tzika, A., Tato, P., Yu, L., Burt, D.W., Bed'hom, B., Tixier-Boichard, M., Painter, K. J., Headon, D. J. Cryptic Patterning of Avian Skin Confers a Developmental Facility for Loss of Neck Feathering. PLoS Biology 9(3): e1001028 (2011)
  • Wells, K., Mou, C., Headon, D. J., Tucker, A. S.Defects and rescue of the minor salivary glands in Eda pathway mutants." Developmental Biology 349(2): 137-146. (2011).
  • Wells, K. L., Mou, C., Headon, D. J. Tucker, A. Recombinant EDA or Sonic Hedgehog rescue the branching defect in Ectodysplasin A pathway mutant salivary glands in vitro. Dev Dyn 239(10): 2674-84. (2010). 
  • Yusvana R, Headon DJ, Markx GH. Creation of arrays of cell aggregates in defined patterns for developmental biology studies using dielectrophoresis. Biotechnol Bioeng. 105(5): 945-954 DOI: 10.1002/bit.22615 (2010).
  • Chang SH, Jobling S, Brennan K*, Headon DJ*. Enhanced Edar signalling has pleiotropic effects on craniofacial and cutaneous glands. PLoS One. 4(10): e7591 (2009)
  • Headon DJ, Painter KJ. Stippling the skin: Generation of anatomical periodicity by reaction-diffusion mechanisms. Mathematical Modelling of Natural Phenomena. 4(4): 83-102 (2009)
  • Heath J, Langton AK, Hammond NL, Overbeek PA, Dixon MJ, Headon DJ. Hair follicles are required for optimal growth during lateral skin expansion. Journal of Investigative Dermatology. 129(10):2358-2364 (2009)
  • Charles C, Pantalacci S, Tafforeau P, Headon D, Laudet V, Viriot L. 2009. Distinct impacts of Eda and Edar loss of function on the mouse dentition. PLoS ONE. 4(4): e4985
  • Headon DJ. 2009. Ectodysplasin signaling in cutaneous appendage development: Dose, duration and diversity. Journal of Investigative Dermatology. 129(4):817-9 Review.
  • Mou C, Thomason HA, Willan PM, Clowes C, Harris WE, Drew CF, Dixon J, Dixon MJ, Headon DJ. 2008. Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form. Hum Mutat. 29(12):1405-11.
  • Langton AK, Herrick SE, Headon DJ. 2008. An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution. J Invest Dermatol. 128(5):1311-8.
  • Headon DJ. 2007. Development of ectodermal appendages. Seminars in Cell and Developmental Biology. 18(2):224 Editorial.
  • Drew CF, Lin CM, Jiang TX, Blunt G, Mou C, Chuong CM, Headon DJ. 2007. The Edar subfamily in feather placode formation. Dev Biol. 305(1):232-45.
  • Mou C, Jackson B, Schneider P, Overbeek PA, Headon DJ. 2006. Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A. 103(24):9075-80.
  • Gazzani S, Lawrenson T, Woodward C, Headon D, Sablowski R. 2004. A link between mRNA turnover and RNA interference in Arabidopsis. Science. 306(5698):1046-8
  • Tucker AS, Headon DJ, Courtney JM, Overbeek P, Sharpe PT. 2004. The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development. Dev Biol. 268(1):185-94.
  • Headon DJ, Emmal SA, Ferguson BM, Tucker AS, Justice MJ, Sharpe PT, Zonana J, Overbeek PA. 2001. Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature. 414(6866):913-6.
  • Hong HK, Noveroske JK, Headon DJ, Liu T, Sy MS, Justice MJ, Chakravarti A. 2001. The winged helix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice. Genesis. 29(4):163-71.
  • Döffinger R, Smahi A, Bessia C, Geissmann F, Feinberg J, Durandy A, Bodemer C, Kenwrick S, Dupuis-Girod S, Blanche S, Wood P, Rabia SH, Headon DJ, Overbeek PA, Le Deist F, Holland SM, Belani K, Kumararatne DS, Fischer A, Shapiro R, Conley ME, Reimund E, Kalhoff H, Abinun M, Munnich A, Israël A, Courtois G, Casanova JL. 2001. X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling. Nat Genet. 27(3):277-85.
  • Tucker AS, Headon DJ, Schneider P, Ferguson BM, Overbeek P, Tschopp J, Sharpe PT. 2000. Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis. Development. 127(21):4691-700.
  • Headon DJ, Overbeek PA. 1999. Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet. 22(4):370-4.
  • Monreal AW, Ferguson BM, Headon DJ, Street SL, Overbeek PA, Zonana J. 1999. Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Nat Genet. 22(4):366-9.