25b0 The Roslin Institute (University of Edinburgh) - Dr Megan Davey
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Developmental Biology

Key references

Stephen, L.A., Davis, G.M., McTeir, K.E., James, J., McTeir, L., Kierans, M., Bain, A., and Davey, M.G. (2013). Failure of centrosome migration causes a loss of motile cilia in TALPID3 mutants. Dev Dyn. E-pub 25 April.

Bangs, F., Antonio N., Thongnuek, P., Welten, M., Davey, M. G., Briscoe, J., Tickle, C. (2011). Generation of mice with functional inactivation of talpid3, a gene first identified in chicken. Development 138(15): 3261-3272.

Dunn IC, Paton IR, Clelland AK, Sebastian S, Johnson EJ, McTeir L, Windsor D, Sherman A, Sang H, Burt DW, Tickle C, Davey MG (2011). The chicken Polydactyly (Po) locus causes allelic imbalance and ectopic expression of Shh during limb development. Dev. Dyn 240(5):1163-72.

Bangs F, Welten M, Davey MG, Fisher M, Yin Y, Downie H, Paton B, Baldock R, Burt DW, Tickle C. (2010) Identification of genes downstream of the Shh signalling in the developing chick wing and syn-expressed with Hoxd13 using microarray and 3D computational analysis. Mech Dev. 127(9-12):428-441.

Cruz, C., Ribes, V., Kutejova, E., Cayuso, J., Lawson, V., Norris, D., Stevens, J., Davey, M., Blight, K., Bangs, F., Mynett, A., Hirst, E., Chung, R., Balaskas, N., Brody, S. L., Marti, E., Briscoe, J. (2010). Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling. Development 137(24): 4271-4282.

Garceau, V., Smith, J., Paton, I. R., Davey, M., Fares, M. A., Sester, D. P., Burt, D. W.
Hume, D. A. (2010). Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. Journal of Leukocyte Biology 87(5): 753-764. 

Macrae VE, Davey MG, McTeir L, Narisawa S, Yadav MC, Millan JL, Farquharson C. (2010) Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick. Bone 1146-55

Yin Y, Bangs F, Paton IR, Prescott A, James J, Davey MG, Whitley P, Genikhovich G, Technau U, Burt DW, Tickle C. (2009). The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation. Development.;136(4):655-64.

Davey MG, Tickle C. (2007). The chicken as a model for embryonic development. Cytogenet Genome Res. 117:231-239

Davey MG, James J, Paton IR, Burt DW, Tickle C. (2007). Analysis of talpid3 and wild-type chicken embryos reveals roles for Hedgehog signalling in development of the limb bud vasculature. Dev Biol. 301(1):155-65.

Davey MG, Paton IR, Yin Y, Schmidt M, Bangs FK, Morrice DR, Gordon Smith T, Buxton P, Stamataki D, Tanaka M, Münsterberg AE, Briscoe J, Tickle C and Burt DW. (2006). The Chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling. Genes and Development 20(10):1365-77

Buxton P, Davey MG, Paton IR, Morrice DR, Francis-West PH, Burt DW, Tickle C. (2004). Craniofacial development in the talpid3 chicken mutant. Differentiation 72(7):348-62.

Davies JA and Davey MG. (1999). Collecting duct morphogenesis. Journal of International Pediatric Nephrology 13(6):535-41.

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