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The Roslin Institute

Developmental Biology

Recent Publications

1. Clinton, M.,Zhao, D., Nandi, S., McBride, D. (2011). Evidence for avian cell autonomous sex identity (CASI) and implications for the sex-determination process? Chromosome Research E-pub 30 November.
2. Zhao D, McBride D, Nandi S, McQueen HA, McGrew MJ, Hocking PM, Lewis PD, Sang HM and Clinton M. Somatic sex identity is cell-autonomous in the chicken. Nature 2010; 464: 237-242.
3. McQueen, H.A. & Clinton, M. Avian sex chromosomes: dosage compensation matters. Chrom. Res. 2009; 17: 687-697.
4. Nandi S, Clinton M. Prospects for sex determination in poultry. 2009 In Biology of breeding poultry 29: 54-59 (ed Hocking PM) Carfax Publishing Company
5. Appleford NE, Wilson K, Houston B, . Clinton M, McGregor I, Anstee DJ. Alpha-Hemoglobin stabilizing protein is not a suitable marker for a screening test for variant Creutzfeldt-Jakob disease. Transfusion 2008; 48(8): 1616-26.
6. Loi P, Matsukawa K, Ptak G, Clinton M, Fulka J Jr, Nathan Y, Arav A. Freeze-dried somatic cells direct embryonic development after nuclear transfer. PLoS ONE. 2008;3(8):e2978.
7. Brown AR, Blanco AR, Miele G, Hawkins SA, Hopkins J, Fazakerley JK, Manson J, Clinton M. Differential expression of erythroid genes in prion disease. Biochem Biophys Res Commun. 2007;364(2):366-71.
8. Loi P, Clinton M, Vackova I, Fulka J Jr, Feil R, Palmieri C, Della Salda L, Ptak G. Placental abnormalities associated with post-natal mortality in sheep somatic cell clones. Theriogenology. 2006;65(6):1110-21.
9. Clinton M, Miele G, Nandi S, McBride D. Identification of disease markers by differential display: prion disease. Methods Mol Biol. 2006;317:157-78.
10. Stylianou IM, Clinton M, Keightley PD, Pritchard C, Tymowska-Lalanne Z, Bünger L, Horvat S. Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways. Physiol Genomics. 2005;20(3):224-32.
11. Larder R, Chang L, Clinton M, Brown P. Gonadotropin-releasing hormone regulates expression of the DNA damage repair gene, Fanconi anemia A, in pituitary gonadotroph cells.Biol Reprod. 2004;71(3):828-36.
12. Stylianou IM, Christians JK, Keightley PD, Bünger L, Clinton M, Bulfield G, Horvat S.
Genetic complexity of an obesity QTL ( Fob3) revealed by detailed genetic mapping. Mamm Genome. 2004;15(6):472-81.
13.Felmer R, Horvat S, Clinton M, Clark AJ. Overexpression of Raidd cDNA inhibits differentiation of mouse preadipocytes. Cell Prolif. 2003;36(1):45-54.
14. Miele G, Alejo Blanco AR, Baybutt H, Horvat S, Manson J, Clinton M. Embryonic activation and developmental expression of the murine prion protein gene. Gene Expr. 2003;11(1):1-12.
15. Ptak G, Clinton M, Tischner M, Barboni B, Mattioli M, Loi P. Improving delivery and offspring viability of in vitro-produced and cloned sheep embryos. Biol Reprod. 2002;67(6):1719-25.
16.Cui W, Aslam S, Fletcher J, Wylie D, Clinton M, Clark AJ. Stabilization of telomere length and karyotypic stability are directly correlated with the level of hTERT gene expression in primary fibroblasts. J Biol Chem. 2002;277(41):38531-9.
17. Loi P, Clinton M, Barboni B, Fulka J Jr, Cappai P, Feil R, Moor RM, Ptak G. Nuclei of nonviable ovine somatic cells develop into lambs after nuclear transplantation. Biol Reprod. 2002; 67(1):126-32.
18. Ptak G, Clinton M, Barboni B, Muzzeddu M, Cappai P, Tischner M, Loi P. Preservation of the wild European mouflon: the first example of genetic management using a complete program of reproductive biotechnologies. Biol Reprod. 2002;66(3):796-801.
19. Miele G, Jeffrey M, Turnbull D, Manson J, Clinton M. Ablation of cellular prion protein expression affects mitochondrial numbers and morphology. Biochem Biophys Res Commun. 2002; 291(2):372-7.
20. Loi P, Ptak G, Barboni B, Fulka J Jr, Cappai P, Clinton M. Genetic rescue of an endangered mammal by cross-species nuclear transfer using post-mortem somatic cells. Nature Biotechnology. 2001;19(10):962-4.
21. Clinton M, Haines L, Belloir B, McBride D. Sexing chick embryos: a rapid and simple protocol. Br Poult Sci. 2001;42(1):134-8.
22. Slee RB, Hillier SG, Largue P, Harlow CR, Miele G, Clinton M. Differentiation-dependent expression of connective tissue growth factor and lysyl oxidase messenger ribonucleic acids in rat granulosa cells. Endocrinology. 2001;142(3):1082-9.
23. Miele G, Manson J, Clinton M. A novel erythroid-specific marker of transmissible spongiform encephalopathies. Nature Medicine. 2001;7(3):361-4.
24. McQueen HA, McBride D, Miele G, Bird AP, Clinton M. Dosage compensation in birds.
Current Biology. 2001;11(4):253-7.
25. Clinton M, Haines LC. An overview of factors influencing sex determination and gonadal development in birds. EXS. 2001;(91):97-115.